^ Robison AJ, Nestler EJ (October 2011). "Transcriptional and epigenetic mechanisms of addiction". Nature Reviews. Neuroscience. 12 (11): 623–37. doi:10.1038/nrn3111. PMC 3272277. PMID 21989194. ΔFosB has been linked directly to several addiction-related behaviors ... Importantly, genetic or viral overexpression of ΔJunD, a dominant negative mutant of JunD which antagonizes ΔFosB- and other AP-1-mediated transcriptional activity, in the NAc or OFC blocks these key effects of drug exposure14,22–24. This indicates that ΔFosB is both necessary and sufficient for many of the changes wrought in the brain by chronic drug exposure. ΔFosB is also induced in D1-type NAc MSNs by chronic consumption of several natural rewards, including sucrose, high fat food, sex, wheel running, where it promotes that consumption14,26–30. This implicates ΔFosB in the regulation of natural rewards under normal conditions and perhaps during pathological addictive-like states.
Alcohol rehab is often the only way that an individual who’s struggling with addiction can get help. There are rehab centers all over the country that offer individualized programs to treat alcoholism, regardless of how long the disease has been present. Alcohol treatment programs take many factors into consideration, including the person’s age and gender, and the extent and length of the addiction. Many alcohol rehab centers also offer various aftercare options and recommendations to help clients maintain their sobriety, such as group therapy.
Assessment and evaluation– Treatment typically begins with a complete physical and psychological assessment to establish which method of rehabilitation should be used. This is completed by both physicians and treatment counselors. Medical and mental health records are read. Family and alcohol-use histories are also reviewed. This process helps to chart the best course of action. Oftentimes, follow-up reviews are necessary to update or adjust treatment measures. Every aspect of care is based on a personalized treatment plan.
Research shows drug use is more common among arrestees than the general population. The Office of National Drug Control Policy reported that 63 to 83 percent of people arrested in five major metropolitan areas in 2013 tested positive for at least one illicit drug. The three most common drugs present during tests were marijuana, cocaine and opiates, and many people tested positive for multiple drugs.
For many people struggling with addiction, the toughest step toward recovery is the very first one: recognizing that you have a problem and deciding to make a change. It’s normal to feel uncertain about whether you’re ready to make a change, or if you have what it takes to quit. If you’re addicted to a prescription drug, you may be concerned about how you’re going to find an alternate way to treat a medical condition. It’s okay to feel torn. Committing to sobriety involves changing many things, including:
Immediately upon entering alcohol rehab, the first step is to undergo a complete diagnostic evaluation. Both physical and psychological, this process is an information-gathering period which will allow the medical team to better formulate a specific treatment plan that will address your individual needs. It is especially important to note acute medical issues brought on by alcohol abuse and co-occurring mental health issues that will require immediate attention.
Individual counseling sessions – These are one-on-one meetings with an addiction treatment counselor. Issues and events that may have contributed toward alcoholism are explored. Patients learn about alcoholism as a disease. They also learn what can trigger addictive thinking and behavior. Vital coping skills are practiced. Healthy routines are developed. They come to understand that an alcohol-free lifestyle takes discipline and dedication.
Addiction is an all-consuming disease, using much of an individual’s time, energy and resources. There are many physical, mental and emotional signs of addiction. If you or a loved one are experiencing a combination of these signs, treatment may be a stepping stone for long-term recovery. Looking for signs and symptoms of drug abuse can be the first step toward identifying an addiction: Inside NHS detox centre - Victoria Derbyshire
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