^ Blum K, Werner T, Carnes S, Carnes P, Bowirrat A, Giordano J, Oscar-Berman M, Gold M (2012). "Sex, drugs, and rock 'n' roll: hypothesizing common mesolimbic activation as a function of reward gene polymorphisms". Journal of Psychoactive Drugs. 44 (1): 38–55. doi:10.1080/02791072.2012.662112. PMC 4040958. PMID 22641964. It has been found that deltaFosB gene in the NAc is critical for reinforcing effects of sexual reward. Pitchers and colleagues (2010) reported that sexual experience was shown to cause DeltaFosB accumulation in several limbic brain regions including the NAc, medial pre-frontal cortex, VTA, caudate, and putamen, but not the medial preoptic nucleus. Next, the induction of c-Fos, a downstream (repressed) target of DeltaFosB, was measured in sexually experienced and naive animals. The number of mating-induced c-Fos-IR cells was significantly decreased in sexually experienced animals compared to sexually naive controls. Finally, DeltaFosB levels and its activity in the NAc were manipulated using viral-mediated gene transfer to study its potential role in mediating sexual experience and experience-induced facilitation of sexual performance. Animals with DeltaFosB overexpression displayed enhanced facilitation of sexual performance with sexual experience relative to controls. In contrast, the expression of DeltaJunD, a dominant-negative binding partner of DeltaFosB, attenuated sexual experience-induced facilitation of sexual performance, and stunted long-term maintenance of facilitation compared to DeltaFosB overexpressing group. Together, these findings support a critical role for DeltaFosB expression in the NAc in the reinforcing effects of sexual behavior and sexual experience-induced facilitation of sexual performance. ... both drug addiction and sexual addiction represent pathological forms of neuroplasticity along with the emergence of aberrant behaviors involving a cascade of neurochemical changes mainly in the brain's rewarding circuitry. How to stop drinking alcohol - how to help an alcoholic
Over time, the patient often comes to believe that the drug betters them as a person and feels incapable of contemplating life without it. In short order, however, use of the drug will begin to cause problems for the user and to remove the good things in their life. All of the perceived “good” effects of using the drug will wear away, but the person will still continue to use, often becoming obsessed with the drug and doing anything they have to do to obtain the substance of choice.
However, it’s important to recognise that you don’t have to suffer on your own; drug addiction is treatable and the most crucial first step is to seek specialist drug addiction treatment and help. Our highly qualified drug addiction teams at Priory consist of expert psychiatrists, psychologists, therapists and other addiction specialists, and we are dedicated to providing personalised, comprehensive drug addiction treatment within our extensive network of hospitals and wellbeing centres.
In 2001, David Sinclair, Ph.D., a researcher in Finland claimed an 80 percent cure rate for alcohol dependence when anti-alcohol drugs Revia or Vivitrol are prescribed according to his Sinclair Method. Dr. Sinclair's research has been published in the peer-reviewed journals Alcohol and Alcoholism and the Journal of Clinical Psychopharmacology. The Sinclair Method is the standard treatment protocol for alcohol dependence in Finland, the method is also used in the U.K., but the method has yet to catch on in the United States. 
As the brain matures, experiences prune excess neural connections while strengthening those that are used more often. Many scientists think that this process contributes to the steady reduction in gray matter volume seen during adolescence (depicted as the yellow to blue transition in the figure). As environmental forces help determine which connections will wither and which will thrive, the brain circuits that emerge become more efficient. However, this is a process that can cut both ways because not all tasks are desirable. The environment is like an artist who creates a sculpture by chipping away excess marble; and just like bad artists can produce bad art, environments with negative factors (like drugs, malnutrition, bullying, or sleep deprivation) can lead to efficient but potentially harmful circuits that conspire against a person's well-being. Coming KLEAN: Stories of Overcoming Addiction, The Documentary (Rated R)
Lastly, drug rehab is important because it affords participants the opportunity to construct new habits. One of the more common characteristics of addicts is poor self-discipline and care. Rehab provides these individuals with the chance not only to set goals but to accomplish them as well. Routinely achieving goals provides addicts with an improved sense of self-worth and resolve.
  I will start out by writing that the Costa Rica Treatment Center has saved my life...I was at rock bottom. Robert and Eric came and picked me up in Jaco, in very bad shape, and they persistently, lovingly, gently, firmly, medicinally, therapeutically, turned me back around, cared for me taught me, changed me...I lived here for one month, and just felt safe and secure. They slowly brought me back to good health. I have grown spiritually, mentally, physically, and emotionally, and can never repay what has been given to me. From Gernot and Maggie (owners of this beautiful home), Robert (administrator, jefe) full of life and play but very disciplined, Eric (assistant manager, wonderful strong, positive, caring energy), Arturo ( Yoga instructor, who gave me daily 5 am classes, with meditation, and a chef), Donia Sonya ( housekeeping), Sheila(psychotherapist), Diego and Marianna(psychologists), Diego (MD), and other persons, in Recovery, who will remain anonymous, who have given their time and advice, and lent an ear to me...I feel this is the best place for you, if you are struggling with an addiction that is out of your control. They just "know" here, how it feels, they understand, without judgement, and their goal is to help you manage your addiction, and move forward into a good life full of purpose, kindness and happiness...This home is beautiful, spacious, room for togetherness and privacy, serene, alcoves, patios, gardens, my room was so cozy, I was able to get much needed rest. I will continue to keep Costa Rica Treatment Center a part of my life, with much gratitude to all of you for returning me to the old, and new Allison...very, very thankful... Russell Brand From Addiction To Recovery

Drug addiction is a growing concern in the United States. People often use drugs as an outlet for their problems, although drug use creates its own problems over time. Drug addiction not only affects a person’s health and relationships, but also impacts society and the environment. There are numerous treatment options to guide people toward a sober and healthy life.


Repeat the focusing with each part of your body that experiences the craving. Describe to yourself the changes that occur in the sensations. Notice how the urge comes and goes. Many people, when they urge surf, notice that after a few minutes the craving has vanished. The purpose of this exercise, however, is not to make the craving go away but to experience the craving in a new way. If you practice urge surfing, you will become familiar with your cravings and learn how to ride them out until they go away naturally.

Work with an intervention specialist. If your loved one is in strong denial about the problem, he or she will probably refuse to get treatment or even to listen to you. A substance abuse counselor or therapist who specializes in intervention can help you plan a formal meeting to confront your loved one with the consequences of their behavior and propose a treatment plan.


Set in the heart of Essex, the facility is close to London and very accessible from the rest of the UK and wider world. Trust your loved ones with us – we will change their lives. The clinic was founded and is operated by people in long-term recovery, and our treatments, facilities and ethos make it the best possible drug & alcohol rehab for you or your loved ones.
People who misuse alcohol are often addicted to the act of drinking, as much as the alcohol itself. For that reason, you may need to learn skills and coping mechanisms to help you avoid alcohol once you leave a treatment center or return to familiar environments where the urge to drink may be stronger. Your doctor may refer you to a counselor or other treatment program to help you learn those skills and coping strategies. Recovery Group Therapy for Drug & Alcohol counseling in South Orange County, CA

Stress, anger, frustration, self-esteem issues, depression, anxiety, trauma – all of these and more can be overwhelming to a person, driving them to seek relief of any kind from any source. Without positive coping skills to help handle issues, many turn to drugs and alcohol and, with repeated use, they spiral out of control into psychological and physical dependence. How to Get Off Opiates (Heroin, oxycodone, fentanyl) | Recovery 2.0 Protocol


You should also speak with an addiction specialist who can give you a wider-range view of treatment options both in your area and further away (some people choose to place quite some distance between their recovery and the environment in which they have been abusing drugs), and who will be able to give you the benefit of more specialised experience and insight than your GP.
Assess how you’re experiencing the craving. Sit in a comfortable chair with your feet flat on the floor and your hands in a relaxed position. Take a few deep breaths and focus your attention inward. Allow your attention to wander through your body. Notice the part of your body where you’re experiencing the craving and what the sensations are like. Tell yourself what it feels like. For example, “My craving is in my mouth and nose and in my stomach.”
Overcoming an alcohol addiction starts with a qualified treatment center that can help address underlying and co-occurring disorders. Because of alcohol’s prevalence throughout our culture, recovering alcoholics are constantly bombarded with triggers. Treatment centers must be equipped to help the recovering user find effective ways to manage triggers and cravings in order to be effective.
One of many recovery methods are 12-step recovery programs, with prominent examples including Alcoholics Anonymous, Narcotics Anonymous, Drug Addicts Anonymous[29] and Pills Anonymous. They are commonly known and used for a variety of addictions for the individual addicted and the family of the individual. Substance-abuse rehabilitation (rehab) centers offer a residential treatment program for some of the more seriously addicted, in order to isolate the patient from drugs and interactions with other users and dealers. Outpatient clinics usually offer a combination of individual counseling and group counseling. Frequently, a physician or psychiatrist will prescribe medications in order to help patients cope with the side effects of their addiction. Medications can help immensely with anxiety and insomnia, can treat underlying mental disorders (cf. self-medication hypothesis, Khantzian 1997) such as depression, and can help reduce or eliminate withdrawal symptomology when withdrawing from physiologically addictive drugs. Some examples are using benzodiazepines for alcohol detoxification, which prevents delirium tremens and complications; using a slow taper of benzodiazepines or a taper of phenobarbital, sometimes including another antiepileptic agent such as gabapentin, pregabalin, or valproate, for withdrawal from barbiturates or benzodiazepines; using drugs such as baclofen to reduce cravings and propensity for relapse amongst addicts to any drug, especially effective in stimulant users, and alcoholics (in which it is nearly as effective as benzodiazepines in preventing complications); using clonidine, an alpha-agonist, and loperamide for opioid detoxification, for first-time users or those who wish to attempt an abstinence-based recovery (90% of opioid users relapse to active addiction within eight months or are multiple relapse patients); or replacing an opioid that is interfering with or destructive to a user's life, such as illicitly-obtained heroin, dilaudid, or oxycodone, with an opioid that can be administered legally, reduces or eliminates drug cravings, and does not produce a high, such as methadone or buprenorphine – opioid replacement therapy – which is the gold standard for treatment of opioid dependence in developed countries, reducing the risk and cost to both user and society more effectively than any other treatment modality (for opioid dependence), and shows the best short-term and long-term gains for the user, with the greatest longevity, least risk of fatality, greatest quality of life, and lowest risk of relapse and legal issues including arrest and incarceration.[citation needed]

^ Volkow ND, Koob GF, McLellan AT (January 2016). "Neurobiologic Advances from the Brain Disease Model of Addiction". N. Engl. J. Med. 374 (4): 363–371. doi:10.1056/NEJMra1511480. PMID 26816013. Substance-use disorder: A diagnostic term in the fifth edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-5) referring to recurrent use of alcohol or other drugs that causes clinically and functionally significant impairment, such as health problems, disability, and failure to meet major responsibilities at work, school, or home. Depending on the level of severity, this disorder is classified as mild, moderate, or severe.
Caring for a person who has problems with alcohol can be very stressful. It is important that as you try to help your loved one, you find a way to take care of yourself as well. It may help to seek support from others, including friends, family, community, and support groups. If you are developing your own symptoms of depression or anxiety, think about seeking professional help for yourself. Remember that your loved one is ultimately responsible for managing his or her illness.
It’s rare for people with alcoholism to strive for that diagnosis. No one grows up wanting to struggle with alcohol for the rest of life. But alcoholism can be sneaky, creeping into life in ways that are subtle and that can pass by unnoticed. For some, alcoholism begins with peer pressure. These people just don’t intend to start drinking, and they may not begin life even enjoying alcohol, but their peers prompt and poke them to drink alcohol. In time, as they comply with these requests from peers, they lose the ability to control how and when they drink.
3. The meat of the program (psychotherapy and behavioral treatments) – This is one of the most important phases of rehabilitation, as it begins to give you a base for future sobriety. During this phase, you work with an alcohol counselor to address your current mental and emotional condition and understand where it’s coming from.  Then, you can start to make behavioral and attitudinal changes to remain sober, prevent relapse, and start living a happy life. If you are dedicated – the chances for your alcohol rehab program to work are increases and you have made significant steps towards becoming sober long-term. Best Drug Rehabilitation Programs Backed By Research. Find Out Why.
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